Criteria for Risk Stratification of Vulvar and Vaginal Smooth Muscle Tumors
نویسندگان
چکیده
منابع مشابه
Diagnostic Value of Proliferatin Index Including MIB1 and Argyrophilic Nucleolar Organizer Regions Proteins in Uterine Smooth Muscle Tumors
Background and Objectives: Uterine smooth muscle tumors are the most common human neoplasm .They are divided clinically as benign and malignant but there is another group of lesions which is difficult to place in these two categories ,so-called smooth muscle tumors of uncertain malignant potential (STUMP) and differentiation of these tumors on the basis of H&E staining is impossible . Th...
متن کاملProposed novel nomenclature of vulvar smooth muscle tumors; a case of Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP) of the vulva
•Clinical experience with smooth muscle tumors of the vulva is limited.•Some tumors present ambiguous histological features concerning for malignancy.•These include infiltration, mitotic activity, size, atypia and tumor cell necrosis.•A case of smooth muscle tumor of the vulva with cellular atypia is presented.•"Smooth Muscle Tumor of Uncertain Malignant Potential" of the vulva is advocated.
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The diagnosis of uterine leiomyosarcoma is usually straightforward since most clinically malignant smooth muscle tumors of the uterus show the microscopic constellation of hypercellularity, severe nuclear atypia, and high mitotic rate generally exceeding 15 mitotic figures per 10 high-power-fields (MF/10 HPF). Frequently, one or more supportive clinicopathologic features such as perior postmeno...
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ژورنال
عنوان ژورنال: American Journal of Surgical Pathology
سال: 2018
ISSN: 0147-5185
DOI: 10.1097/pas.0000000000000920